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ea0049gp198 | Thyroid 1 | ECE2017

Which is the best tool to use when initiating the differential diagnosis of a thyrotoxic patient? A challenge to current guideline recommendations

Perdomo Carolina , Ramos Elisa Gil , Buey Gala Gutierrez , Llavero Maria , Gargallo Javier , Arbizu Javier , de la Higuera Magdalena , Galofre Juan C

Aim: Differential diagnosis (DD) of thyrotoxicosis is critical as the treatment of the three main causes of this condition (Graves disease [GD], Toxic Multinodular Goitre [TMG], and Thyroiditis [TS]) differs substantially. Recently published diagnostic algorithms investigating hyperthyroidism embrace the presence of thyrotropin receptor (TSH-R) antibodies (TRab) as the first and most cruicial diagnostic step. Although TRab measurement has important limitations (some can ...

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ea0056p1048 | Thyroid (non-cancer) | ECE2018

Correlation of recommended diagnostic tools with pathological findings in the thyrotoxic patient

Perdomo Carolina M , Paricio Jose Joaquin , Llavero Maria , Gargallo Javier , Garcia Marta , Miralles Raquel , Morales Maria I , Alcalde Juan , Idoate Miguel Angel , Arbizu Javier , Galofre Juan C

Aim: A key diagnostic step to determine the cause of hyperthyroidism is the measurement of circulating thyroid-stimulating immunoglobulin (TSI). High levels are associated with Graves disease (GD). A thyroid scintigraphy (TRS) is recommended when TSI is absent or its measurement unavailable, as TRS is capable of differentiating between GD (diffuse uptake) and toxic goitre (TG) (patchy uptake). Nevertheless, and while rarely necessary, histopathology remain the best metho...

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Endocrine Abstracts

Which is the best tool to use when initiating the differential diagnosis of a thyrotoxic patient? A challenge to current guideline recommendations

Correlation of recommended diagnostic tools with pathological findings in the thyrotoxic patient

BiosciAbstracts